17 Hydroxyprogesterone Test: Screen for CAH

The 17-Hydroxyprogesterone Test is a medical tool to check for a genetic condition called congenital adrenal hyperplasia (CAH) and assess its treatment progress. It helps doctors ensure healthy hormone levels in patients.

17 Hydroxyprogesterone Test

Here are the basic details of the 17 Hydroxyprogesterone Test.

*Price range may vary as per location, lab type, and procedure of lab test.

17 Hydroxyprogesterone Test Means

The 17 Hydroxyprogesterone Test measures a hormone called 17-OHP in the blood.

• It's used to screen for congenital adrenal hyperplasia (CAH) and monitor CAH treatment.
• This test can help detect and manage hormone imbalances.
• It's a valuable tool for infants with ambiguous genitalia and individuals with CAH symptoms.
• Results guide treatment decisions and ensure hormone levels are within a healthy range.

17 Hydroxyprogesterone Test Purpose

The purpose of the 17 Hydroxyprogesterone Test is to:

• Detect congenital adrenal hyperplasia (CAH), a genetic disorder.
• Tracks treatment effectiveness by evaluating hormone levels.
• Assists in diagnosing CAH in individuals with symptoms or ambiguous genitalia.
• Ensures healthy hormone levels, preventing complications related to CAH.
• Vital for newborns with potential CAH to start treatment early, promoting healthy development.

17 Hydroxyprogesterone Test Preparation

Here is the basic preparation for the 17 Hydroxyprogesterone Test.

Before Test

• Usually, no specific preparation is needed.
• Inform your healthcare provider about any medications or supplements you're taking.
• Follow any fasting or timing instructions provided.

During Test

• A blood sample will be drawn from a vein or obtained from a heelstick (for infants).
• The procedure is relatively quick and minimally uncomfortable.

After Test

• You can resume regular activities immediately.
• Results will be reported to your healthcare provider for interpretation and discussion.

17 Hydroxyprogesterone Test Procedure

Here is the basic 17 Hydroxyprogesterone Test Procedure.

• Blood sample drawn from a vein or heelstick (for infants).
• Needle insertion may cause brief discomfort.
• Collected sample is sent to a lab for analysis.
• Results interpreted by healthcare provider.
• Typically a quick and straightforward procedure.

17 Hydroxyprogesterone Test Result

• Elevated levels suggest possible congenital adrenal hyperplasia (CAH).
• Normal levels indicate no significant CAH-related hormone imbalance.
• Interpretation by healthcare provider is necessary to guide further evaluation or treatment.

17 Hydroxyprogesterone Test Normal Range

Here is the normal range of the 17 Hydroxyprogesterone Test.

17 Hydroxyprogesterone Test Interpretation

Here is the Interpretation of the 17 Hydroxyprogesterone Test.

Elevated 17-OHP may indicate possible CAH, while normal levels suggest no significant hormone imbalance.

17 Hydroxyprogesterone Test High Levels

Here are some possible causes of high Hydroxyprogesterone levels:

High 17-OHP levels can result from CAH, adrenal or ovarian tumors, and late-onset CAH.

17 Hydroxyprogesterone Test Low Levels

Here are some possible causes of low Hydroxyprogesterone levels:

Low 17-hydroxyprogesterone levels may result from cortisol replacement therapy, adrenal insufficiency, or genetic enzyme deficiencies.

Specimen Requirements For 17 Hydroxyprogesterone Test

Here are the specimen requirements for the 17 Hydroxyprogesterone Test.

17 Hydroxyprogesterone Test is Safe?

17 Hydroxyprogesterone Test is generally safe and minimally invasive blood test.

• Standard medical procedure with low risk.
• Rarely, minor discomfort or bruising at the needle insertion site.

When Do You Get 17 Hydroxyprogesterone Test Results? 

• 17 Hydroxyprogesterone test results typically available 24 hours after birth.
• Provides timely information for early diagnosis if needed.
• Enables prompt management and treatment if congenital adrenal hyperplasia (CAH) is suspected.

17 Hydroxyprogesterone Test Limitation

Here is the basic limitation of 17 Hydroxyprogesterone Test.

• Limited specificity for CAH diagnosis.
• Interpretation can be complex.
• May require additional confirmatory tests.
• Levels influenced by various factors.
• False positives and negatives possible.

17 Hydroxyprogesterone Test Risk Factors

Here are some of the risk factors of the 17 Hydroxyprogesterone Test.

• Family history of congenital adrenal hyperplasia (CAH) increases the risk of inheriting the condition.
• Certain genetic mutations can predispose individuals to CAH.
• Consanguineous (closely related) parents have a higher risk of having children with CAH.
• Ethnicity plays a role; CAH is more common in certain populations.
• Maternal exposure to specific medications or environmental factors during pregnancy may increase CAH risk.

Doctor Recommendations After 17 Hydroxyprogesterone Test Result

 Here are the Doctor's recommendations or consult a specialist after the 17 Hydroxyprogesterone Test.

Visit an endocrinologist for high 17-OHP results indicating possible CAH; for normal or low results, no specific doctor visit is necessary.

17 Hydroxyprogesterone Test Price

Here are the estimated 17 Hydroxyprogesterone Test Prices in India with different top cities:

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

Summary

Overall, The 17 Hydroxyprogesterone Test screens for congenital adrenal hyperplasia (CAH) and monitors hormone levels, helping diagnose and manage this genetic disorder. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

Reference

• Newborn screening - Wikipedia [1].
• High 17-hydroxyprogesterone level in newborn screening ... - NIH [2].