Antibiotic Susceptibility Testing For Bacterial Infection

Antibiotic Susceptibility Testing For Bacterial Infection

The Antibiotic Susceptibility Testing determines which antibiotics are effective against a specific bacterial infection, guiding doctors in prescribing the right treatment.

 

Antibiotic Susceptibility Testing

Here are the basic details of the Antibiotic Susceptibility Testing.

Also Known As Antibiotic Sensitivity Test
Type Microbiological Test
Purpose Determine Effective Antibiotics
Sample Type Bacterial Culture
Preparation Bacterial Isolation
Fasting Not Applicable
Gender All
Age Group All
Normal Value Varies by Bacterial Strain
Reporting Time 1-2 days
Cost 5000-7000 INR*

*Antibiotic Susceptibility Testing Price range may vary as per location, lab type, and procedure of lab test.

 

Antibiotic Susceptibility Testing Means

The Antibiotic Susceptibility Testing, also known as a bacterial culture and sensitivity test, assesses how bacteria respond to specific antibiotics.

  • It is essential for guiding the choice of antibiotics to treat bacterial infections.
  • The test helps identify the most effective antibiotic for eradicating a particular infection.
  • Results guide healthcare providers in prescribing the most appropriate antibiotic therapy.
  • Antibiotic Susceptibility Testinging is crucial for preventing antibiotic resistance.
  • It ensures that patients receive the most targeted and effective treatment against bacterial infections.

 

Antibiotic Susceptibility Testing Purpose

The purpose of the Antibiotic Susceptibility Testing is to:

  • Determine how bacteria respond to specific antibiotics.
  • Identify the most effective antibiotic for treating bacterial infections.
  • Guide healthcare providers in antibiotic prescription.
  • Prevent the development of antibiotic resistance.
  • Ensure patients receive targeted and effective antibiotic treatment.
  • Improve the outcome of bacterial infection treatments.

Antibiotic Susceptibility Testing- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Antibiotic Susceptibility Testing Preparation

Here is the basic preparation for the Antibiotic Susceptibility Testing.

 

Before Test

  • Consult with your healthcare provider to understand the purpose of the test and any specific instructions.
  • Inform your healthcare provider about any antibiotics you have taken recently or any ongoing antibiotic treatment.
  • If you are providing a urine or other sample, follow any instructions provided for proper collection, such as cleanliness and timing.

 

During Test

  • The test may involve providing a sample of blood, urine, or other bodily fluids. Cooperate with the healthcare professional or laboratory technician during the sample collection process.
  • Follow any additional instructions regarding the collection, handling, and transport of the sample.
  • If you have any questions or concerns during the test, don't hesitate to ask the healthcare provider or technician for clarification.

 

After Test

  • Await the test results, which may take some time to process, depending on the laboratory's procedures.
  • Schedule a follow-up appointment to discuss the test results with your healthcare provider. They will help interpret the results and recommend appropriate antibiotics if needed.
  • Follow your healthcare provider's guidance regarding antibiotic treatment, dosage, and duration, and report any adverse effects or concerns during treatment.

 

Antibiotic Susceptibility Testing Procedure

Here is the basic Antibiotic Susceptibility Testing Procedure.

  • A biological sample, such as blood or a swab, may be taken, depending on the infection being tested.
  • The sample collection method can vary but is generally tolerable.
  • The process is usually quick.
  • Patients may experience anxiety while awaiting test results.
  • Your healthcare provider will discuss the results and prescribe appropriate antibiotics.
  • Patients might feel anxious about the results and the need for antibiotics, but the test procedure is usually straightforward.

 

Antibiotic Susceptibility Testing Result

Here is the basic meaning of Antibiotic Susceptibility Testing Result.

  • Sensitive: If the bacteria are sensitive to the antibiotic tested, it means the antibiotic is likely to be effective in treating the infection.
  • Resistant: Resistance indicates that the bacteria won't respond well to the tested antibiotic, and an alternative treatment may be needed.
  • Intermediate: Intermediate results mean the antibiotic may work, but it's not the best choice.
  • Consult a Physician: The choice of antibiotics should be made in consultation with a healthcare provider, considering the specific bacteria and infection.

 

Antibiotic Susceptibility Testing Normal Result

Here is the normal result of the Antibiotic Susceptibility Testing

Result Meaning
Susceptible The bacteria are susceptible to the tested antibiotic, indicating that it should be effective in treating the infection.

 

Antibiotic Susceptibility Testing Interpretation

Here is the Interpretation of the Antibiotic Susceptibility Testing.

Interpretation Meaning
Susceptible The bacteria are vulnerable to the antibiotic, and it should be effective in treating the infection.
Intermediate The antibiotic may have limited effectiveness, and the choice of antibiotic should be carefully considered.
Resistant The bacteria are not affected by the antibiotic, and an alternative treatment should be pursued.

 

Antibiotic Susceptibility Testing Intermediate Result

Here are the potential causes of Intermediate results (Limited Effectiveness) in Antibiotic Susceptibility Testing.

Potential Causes Explanation
Low Antibiotic Concentration The antibiotic concentration may be below the effective therapeutic range.
Borderline Bacterial Susceptibility The bacteria may have reduced sensitivity to the antibiotic, and its effectiveness is uncertain.
Mutation or Resistance Mechanisms The bacteria may have developed mechanisms to limit the antibiotic's effectiveness.
Suboptimal Antibiotic Choice The antibiotic selected may not be the most appropriate for the specific bacterial strain.
Testing Method Variability Variations in testing methods or conditions may lead to an intermediate result.

 

Antibiotic Susceptibility Testing Resistant Result

Here are the potential causes of Resistant result (Ineffective) in Antibiotic Susceptibility Testing.

Potential Causes Explanation
High Bacterial Resistance The bacteria have developed strong resistance to the antibiotic, rendering it ineffective.
Specific Resistance Mechanisms Bacteria may possess specific genetic mutations or resistance mechanisms against the antibiotic.
Inappropriate Antibiotic Selection The chosen antibiotic is not effective against the particular bacterial strain.
Antibiotic Overuse or Misuse Previous misuse or overuse of antibiotics may contribute to bacterial resistance.
Inadequate Antibiotic Concentration The antibiotic concentration is insufficient to inhibit bacterial growth.

 

Specimen Requirements For Antibiotic Susceptibility Testing

Here are the specimen requirements for the Antibiotic Susceptibility Testing.

Specimen Sufficient to perform bacterial culture (varies by laboratory).
Container Sterile container (e.g. a culture tube or blood culture bottle).
Collection Aseptic technique for specimen collection.
Storage Store at an appropriate temperature during transit (typically 2-8°C or per laboratory guidelines).
Sample Stability Typically, specimens should be processed within 24 hours of collection.
Causes for Rejection
  • Inadequate specimen volume or contamination.
  • Delayed transport or inappropriate storage.
  • Specimen not labelled properly or missing patient information.
  • Specimens from non-sterile sources.

 

Antibiotic Susceptibility Testing is Safe?

  • Safe Laboratory Test: The test is conducted in a laboratory and doesn't pose risks to the patient.
  • No Direct Patient Risk: Patients are not directly exposed to risks associated with this test.
  • Important for Treatment: Antibiotic Susceptibility Testinging is crucial for safe and effective treatment of bacterial infections. Consult your healthcare provider for appropriate antibiotic choices based on the results.

 

When Do You Get Antibiotic Susceptibility Testing Results? 

  • Usually provided within 1 to 2 days.
  • Time may vary depending on the specific bacteria being tested and the laboratory's capabilities.

 

Antibiotic Susceptibility Testing Limitation

Here is the basic limitation of Antibiotic Susceptibility Testing.

  • Results may take time, delaying treatment decisions.
  • Limited to specific strains of bacteria tested.
  • Doesn't account for host factors affecting drug response.
  • Resistance patterns can change over time.
  • May not address the overall health condition of the patient.

 

Antibiotic Susceptibility Testing Risk Factors

Here are some of the risk factors of the Antibiotic Susceptibility Testing.

  • Frequent or recent antibiotic use increases resistance risk.
  • Hospital or healthcare facility stays.
  • Exposure to drug-resistant bacteria.
  • Weakened immune system (e.g., due to illness or medications).
  • Recent travel to areas with high antibiotic resistance.

 

Doctor Recommendations After Antibiotic Susceptibility Testing Result

 Here are the Doctor's recommendations or consult a specialist after the Antibiotic Susceptibility Testing.

Result Doctor to Visit Reason to Visit
Susceptible General Practitioner Discuss antibiotic treatment.
Intermediate Infectious Disease Specialist Seek expert advice on treatment.
Resistant Infectious Disease Specialist Explore alternative treatments.

 

Antibiotic Susceptibility Testing Price

Here are the estimated Antibiotic Susceptibility Testing Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

5000-7000

New Delhi

5500-7000

Bangalore

5000-7000

Hyderabad

5500-7000

Kolkata

5000-7000

Pune

5500-7000

Lucknow

5000-7000

Noida

5500-7000

Surat

5500-7000

Gurugram

5000-7000

Patna

5500-7000

Chennai

5000-7000

Jaipur

5500-7000

Ahmedabad

5000-7000

*Antibiotic Susceptibility Testing Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Antibiotic Susceptibility Testing is critical for guiding effective antibiotic treatment, preventing antibiotic resistance, and improving patient care. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Antibiotic Susceptibility Testing - Wikipedia [1].
  • Antibiotic Susceptibility Testing - NIH [2].

 

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FAQ

What is Antibiotic Susceptibility Testing?

Antibiotic Susceptibility Testing is a laboratory technique used to determine the effectiveness of antibiotics against specific bacterial or fungal infections. It helps guide clinicians in choosing the most appropriate treatment.

Why is Antibiotic Susceptibility Testing important?

Antibiotic Susceptibility Testing is crucial because it helps in tailoring antibiotic treatment to the specific pathogen causing an infection, reducing the risk of treatment failure and the development of antibiotic resistance.

How does Antibiotic Susceptibility Testing work?

Antibiotic susceptibility tests involve growing the infectious agent in the presence of different antibiotics to see which one inhibits its growth. The results are interpreted as "sensitive," "intermediate," or "resistant."

How long does it take to get Antibiotic Susceptibility Testing results?

The time varies depending on the method used, but it can take anywhere from 24 hours to several days to obtain results. Faster methods like E-test or automated systems may yield results more quickly.

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