Factor VIII (Antihemophilic Factor A) Test To Diagnose Hemophilia A

The Factor VIII Test measures the levels of factor VIII in the blood, a critical protein for blood clotting, and is primarily used to diagnose and monitor hemophilia A.

Factor VIII Test

Here are the basic details of the Factor VIII Test.

Test Name	Factor VIII Test
Also Known As	Antihemophilic Factor A Test
Type	Coagulation
Purpose	Measure Factor VIII levels in the blood
Sample Type	Blood plasma
Preparation	Fasting may be required
Gender	Any
Age Group	All ages
Normal Value	50-150% of normal levels
Reporting Time	Few Days
Cost	2000-3000 INR*

*Factor VIII Test Price range may vary as per location, lab type, and lab test procedure.

Factor VIII Test Means

The Factor VIII test, also known as Antihemophilic Factor A assay, is a laboratory examination that measures the concentration of factor VIII in the blood.

Factor VIII is a critical coagulation protein, and its deficiency is the primary cause of hemophilia A.
This test helps diagnose and monitor hemophilia A and assess the severity of the condition.
Factor VIII levels are essential in determining the appropriate treatment and factor replacement therapy.
Accurate measurement of factor VIII is vital for personalized care and treatment planning in hemophilia patients.
This test aids in preventing and managing bleeding episodes in individuals with hemophilia A.

Factor VIII Test Purpose

The purpose of the Factor VIII Test is to:

Measures the concentration of factor VIII in the blood.
Diagnoses and monitors hemophilia A, a bleeding disorder.
Determines the severity of hemophilia and guides treatment.
Ensures personalized care and factor replacement therapy.
Prevents and manages bleeding episodes in hemophilia patients.

Factor VIII Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

Factor VIII Test Preparation

Here is the basic preparation for the Factor VIII Test.

Before Test

Follow any pre-test instructions provided by your healthcare provider, such as fasting or medication adjustments.
Be prepared to share your medical history, particularly any history of bleeding episodes or clotting disorders.
Discuss any concerns or questions you have about the test with your healthcare provider to ensure you are well-informed.

During Test

Cooperate with the healthcare team during the blood sample collection process, which typically involves a simple blood draw.
If you experience discomfort or anxiety during the venipuncture, communicate your concerns with the phlebotomist or healthcare provider.
Remain as still as possible to ensure a successful blood sample collection.

After Test

Allow the healthcare team to process the blood sample and conduct the Factor VIII test.
Inquire about the expected timeline for receiving your test results and any potential follow-up steps.
Resume your regular activities unless your healthcare provider advises otherwise.

Factor VIII Test Procedure

Here is the basic Factor VIII Test Procedure.

Draw a blood sample from the patient's vein using sterile equipment.
Centrifuge the blood to separate the plasma from cellular components.
In the laboratory, perform a coagulation assay using the patient's plasma.
Assess the concentration of factor VIII in the plasma.
Results are reported as a numerical value representing factor VIII levels.
Abnormal factor VIII levels assist in diagnosing and managing hemophilia A.

Factor VIII Test Result

Here is the basic reading of the Factor VIII Test results.

Factor VIII test results are reported as a numerical value in international units per deciliter (IU/dL), indicating the concentration of factor VIII in the blood.
Lower factor VIII levels suggest a greater severity of hemophilia A, a condition associated with impaired clotting.
Normal or near-normal factor VIII levels are expected in individuals without hemophilia A.
Factor VIII results play a critical role in diagnosing and managing hemophilia A and determining appropriate treatment strategies.

Factor VIII Test Normal Result Report

Factor VIII Antihemophilic Factor A Test Normal Result Report Format - Drlogy Test

Factor VIII Test Normal Report

Factor VIII Test Normal Result Report PDF

Factor VIII Test Abnormal Result Report

Factor VIII Antihemophilic Factor A Test Abnormal Result Report Format - Drlogy Test

Factor VIII Test Abormal Report

Factor VIII Test Abnormal Result Report PDF

Factor VIII Test Normal Range

Here is the normal range of the Factor VIII Test.

Age Group	Normal Range for Factor VIII (%)
Adults	50 - 150

Factor VIII Test Interpretation

Here is the Interpretation of the Factor VIII Test.

Factor VIII Level	Interpretation
Below 50%	May indicate a Factor VIII deficiency or hemophilia.
50% - 150%	Indicates a typical level of Factor VIII.
Above 150%	Elevated Factor VIII may be associated with a prothrombotic state.

Factor VII Activity High Levels

Here are the potential causes of high Factor VIII Test levels:

Potential Causes	Explanation
Hypercoagulable State	Excessive blood clotting, increased Factor VII activity.
Liver Disease	Liver dysfunction can affect clotting factor production.
Medications	Some medications or therapies can increase Factor VII activity.
Vitamin K Deficiency	Vitamin K is essential for normal clotting factor production.
Hereditary Conditions	Rare genetic disorders can result in increased Factor VII activity.

Factor VII Activity Low Levels

Here are the potential causes of low Factor VIII Test levels:

Potential Causes	Explanation
Liver Disease	Liver dysfunction may decrease clotting factor production.
Vitamin K Deficiency	Vitamin K is necessary for the synthesis of clotting factors.
Bleeding Disorders	Conditions that affect clotting factor production or function.
Medications	Certain medications can reduce Factor VII activity.
Genetic Disorders	Rare genetic conditions may result in reduced Factor VII activity.

Specimen Requirements For Factor VIII Test

Here are the specimen requirements for the Factor VIII Test.

Specimen	Blood Plasma
Volume	1 mL
Container	Na Cit
Collection	Plasma Na Cit
Storage	Room temperature
Sample Stability	Temperature	Period
	Frozen	14 days
Causes for Rejection	Gross hemolysis, Gross lipemia, and Gross icterus

Factor VIII Test is Safe?

The Factor VIII Test is considered safe and involves a routine blood sample collection.

It poses minimal risks to patients, primarily associated with venipuncture, such as mild bruising or discomfort.
Patients with specific clotting disorders, like hemophilia, may experience increased bleeding risk with blood draws, but this can be managed by experienced healthcare providers.

When Do You Get Factor VIII Test Results?

Factor VIII (Antihemophilic Factor A) Test results are typically accessible within a few days, depending on the laboratory's testing schedule.
Patients should consult their healthcare provider or the testing facility for precise information about when they can expect the results.

Factor VIII Test Limitation

Here is the basic limitation of the Factor VIII Test.

Limited utility in diagnosing the severity of hemophilia A.
Doesn't provide information on other clotting factors or potential bleeding disorders.
Results may be affected by the timing of the test in relation to factor VIII infusions.
Cannot differentiate between inherited and acquired factor VIII deficiencies.
Interpretation can vary between different laboratories and methods.

Factor VIII Test Risk Factors

Here are some of the risk factors of the Factor VIII Test.

Risk factors for low Factor VIII levels are mainly associated with hemophilia A, a genetic bleeding disorder.
Inhibitors, which are antibodies that neutralize Factor VIII, can impact test results.
Hemorrhagic diseases or liver disease may affect Factor VIII levels.
Timing of the test in relation to Factor VIII infusions can influence results.
Interpretation should consider the patient's medical history, medications, and known bleeding risk factors.

Doctor Recommendations After Factor VIII Test Result

Here are the Doctor's recommendations or consult a specialist after the Factor VIII Test.

Factor VIII Test Result	Doctor to Visit	Reason for Visit
High	Hematologist	Evaluate clotting disorder
Normal	General Doctor	Routine assessment
Low	Hematologist	Investigate clotting abnormalities

Factor VIII Test Price

Here are the estimated Factor VIII Test Prices in India with different top cities:

City	Price Range (INR)*
Mumbai	2000-3000
New Delhi	2200-3000
Bangalore	2000-3000
Hyderabad	2200-3000
Kolkata	2000-3000
Pune	2200-3000
Lucknow	2000-3000
Noida	2200-3000
Surat	2200-3000
Gurugram	2000-3000
Patna	2200-3000
Chennai	2000-3000
Jaipur	2200-3000
Ahmedabad	2000-3000

*Factor VIII Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

Summary

Overall, Factor VIII Test is of critical importance as it helps diagnose and monitor hemophilia A, a severe bleeding disorder, enabling timely intervention, treatment, and improved quality of life for affected individuals. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

Reference

Factor VIII Test - Wikipedia [1].
Factor VIII Test - NIH [2].

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What is a factor VIII test?

A factor VIII test measures the level of factor VIII in the blood. Factor VIII is a clotting protein essential for blood coagulation.

What is a normal factor VIII level?

A normal factor VIII level typically ranges from 50% to 150% of the normal range, where 100% is considered the average.

How do you treat high factor VIII?

High factor VIII is usually associated with clotting disorders. Treatment involves managing underlying conditions, such as anticoagulant therapy or addressing the cause.

Why is factor VIII high?

High factor VIII levels can be caused by various factors, including genetics, inflammation, liver disease, or certain medical conditions. Elevated levels may increase the risk of clotting.

What is factor VIII in vWF?

Factor VIII is often found in complex with von Willebrand factor (vWF) in the blood. These two proteins work together to promote blood clotting, with vWF helping to stabilize and protect factor VIII.