Ganglioside GD1b Antibody IgM Test For Neurological Conditions

Ganglioside GD1b Antibody IgM Test For Neurological Conditions

Ganglioside GD1b Antibody IgM Test is a medical assessment that looks for specific antibodies called IgM related to nerve and muscle functions in the bloodstream. This test is used to diagnose neurological conditions that can impact muscle strength and nerve signaling.

 

Ganglioside GD1b Antibody IgM Test

Here are the basic details of the Ganglioside GD1b Antibody IgM Test.

Test Name Ganglioside GD1b Antibody IgM Test
Also Known As GD1b IgM Test
Type Antibody Test
Purpose Neuropathy diagnosis
Sample Type Blood
Preparation None
Fasting Not required
Gender All
Age Group All
Normal Value Negative
Reporting Time Few Days
Cost 2000-5000 INR*

*Ganglioside GD1b Antibody IgM Test Price range may vary as per location, lab type, and lab test procedure.

 

Ganglioside GD1b Antibody IgM Test Means

Ganglioside GD1b Antibody IgM Test checks for IgM antibodies against Ganglioside GD1b.

  1. Gangliosides are molecules present in nerve cell membranes.
  2. IgM antibodies are immune proteins that can target these gangliosides.
  3. Elevated IgM levels may be associated with neurological or autoimmune disorders.
  4. The test is useful for diagnosing conditions like Guillain-Barré syndrome.
  5. It aids in the assessment of nerve-related and autoimmune diseases.

 

Ganglioside GD1b Antibody IgM Test Purpose

The purpose of the Ganglioside GD1b Antibody IgM Test is to:

  • Assist in diagnosing disorders such as Guillain-Barré syndrome.
  • Evaluate autoimmune and neurological conditions.
  • Detect IgM antibodies against Ganglioside GD1b.
  • Support the assessment of nerve-related and autoimmune diseases.
  • Contribute to identifying the underlying cause of neurological symptoms.
  • Guide treatment decisions based on test results.

Ganglioside GD1b Antibody IgM Test- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Ganglioside GD1b Antibody IgM Test Preparation

Here is the basic preparation for the Ganglioside GD1b Antibody IgM Test.

 

Before Test

  • Comply with any fasting or dietary instructions provided by your healthcare provider.
  • Inform your healthcare provider about all medications and supplements you are taking.
  • Be prepared to discuss your medical history and any relevant symptoms.

 

During Test

  • Stay relaxed and cooperate with the healthcare professional conducting the blood draw.
  • Communicate any discomfort or unusual sensations during the procedure.
  • Follow any additional instructions provided by the healthcare provider.

 

After Test

  • Avoid strenuous activities and heavy lifting immediately after the blood draw.
  • Keep the bandage in place on the puncture site for the recommended time.
  • Await communication from your healthcare provider regarding the test results and any necessary follow-up.

 

Ganglioside GD1b Antibody IgM Test Procedure

Here is the basic Ganglioside GD1b Antibody IgM Test Procedure.

  • Schedule the test with your healthcare provider.
  • Comply with any pre-test instructions given.
  • Have a blood sample drawn at the testing site.
  • The blood sample is sent to a laboratory for analysis.
  • Await test results, which will be provided by your healthcare provider.
  • Follow up with your healthcare provider for interpretation and next steps.

 

Ganglioside GD1b Antibody IgM Test Result

Here is the basic reading of the Ganglioside GD1b Antibody IgM Test results.

  • Positive Result: Detection of IgM antibodies against Ganglioside GD1b may be associated with conditions such as Guillain-Barré syndrome or other neurological disorders.
  • Negative Result: No IgM antibodies against Ganglioside GD1b are found, indicating an absence of specific immune response to this ganglioside.
  • Titer Level: The titer level quantifies the amount of IgM antibodies present, with a higher titer suggesting a stronger immune response.
  • Consult Healthcare Provider: Discuss your test results with a healthcare provider who will consider your medical history and symptoms in the context of the results.

 

Ganglioside GD1b Antibody IgM Test Normal Result

Here is the normal result of the Ganglioside GD1b Antibody IgM Test.

Test Name Normal Result Meaning of Result
Ganglioside GD1b Antibody IgM Test Negative No significant IgM antibodies were found.

 

Ganglioside GD1b Antibody IgM Test Interpretation

Here is the Interpretation of the Ganglioside GD1b Antibody IgM Test.

Results Interpretation
Positive IgM antibodies detected (abnormal).
Negative No IgM antibodies were detected (normal).

 

Ganglioside GD1b Antibody IgM Test Positive Result

Here are the potential causes of Positive Result of GD1b Antibody IgM Test.

Positive Results Potential Causes
Sensory ataxic neuropathy Autoimmune neuropathy
Miller Fisher Syndrome Immune-related neurological disorders
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Neuropathic conditions
Bickerstaff Brainstem Encephalitis Sensory motor neuropathies
Other autoimmune neuropathies Neurological complications

 

Ganglioside GD1b Antibody IgM Test Negative Result

Here are the potential causes of Negative Result of Ganglioside GD1b Antibody IgM Test levels:

Negative Results Potential Causes
Absence of neurological disorder Different types of antibody present
Other immune-related disorders Incomplete antibody panel tested
Normal immune response The early stage of the neurological condition
Non-neurological conditions Antibody levels below the detection limit
Insufficient antibodies present Antibody test sensitivity or specificity issues

 

Specimen Requirements For Ganglioside GD1b Antibody IgM Test

Here are the specimen requirements for the Ganglioside GD1b Antibody IgM Test.

Specimen

Serum

Volume

1 mL

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer the separated serum to a plastic transport tube.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x6

Causes for Rejection

Sample type other than serum received.

 

Ganglioside GD1b Antibody IgM Test is Safe?

The Ganglioside GD1b Antibody IgM Test is generally safe for most individuals.

  • Minor discomfort or bruising at the blood collection site may be the main risks.
  • Patients should discuss any concerns with their healthcare provider before undergoing the test.

 

When Do You Get Ganglioside GD1b Antibody IgM Test Results? 

  • Ganglioside GD1b Antibody IgM test results are usually available within a few days to a week after the blood sample is collected.
  • The specific timing may vary based on the laboratory's processing schedule and the healthcare facility's procedures.

 

Ganglioside GD1b Antibody IgM Test Limitation

Here is the basic limitation of the Ganglioside GD1b Antibody IgM Test.

  • Potential for false negatives, especially in specific neurological conditions.
  • Limited sensitivity for rare disorders.
  • Cannot identify the precise cause of symptoms.
  • Results may not provide insight into disease severity or progression.
  • Cross-reactivity with other antibodies may affect interpretation.
  • Clinical correlation and additional testing may be required for accuracy.

 

Ganglioside GD1b Antibody IgM Test Risk Factors

Here are some of the risk factors of the Ganglioside GD1b Antibody IgM Test.

  • Low-risk factors are typically associated with this test.
  • Minor discomfort or bruising at the blood collection site is possible.
  • Risks may be higher for individuals with bleeding disorders.
  • Allergic reactions to the test components are a potential concern.
  • Adherence to standard safety protocols is essential.

 

Doctor Recommendations After Ganglioside GD1b Antibody IgM Test Result

 Here are the Doctor's recommendations or consult a specialist after the Ganglioside GD1b Antibody IgM Test.

Test Result Doctor to Visit Reason to Go
Positive Neurologist Assess neurological condition.
Negative Consult as needed Depending on symptoms or issues.

 

Ganglioside GD1b Antibody IgM Test Price

Here are the estimated Ganglioside GD1b Antibody IgM Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

2000-5000

New Delhi

2500-5000

Bangalore

2000-5000

Hyderabad

2500-5000

Kolkata

2000-5000

Pune

2500-5000

Lucknow

2000-5000

Noida

2500-5000

Surat

2500-5000

Gurugram

2000-5000

Patna

2500-5000

Chennai

2000-5000

Jaipur

2500-5000

Ahmedabad

2000-5000

*Ganglioside GD1b Antibody IgM Test Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Ganglioside GD1b Antibody IgM Test helps diagnose specific neurological conditions. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Antiganglioside antibodies Anti-GD1b - Wikipedia [1].
  • Clinical and Diagnostic Role of Ganglioside Antibody Testing- NIH [2].
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FAQ

What is ganglioside antibody test for?

Ganglioside antibody tests are used to detect antibodies that target gangliosides, which are glycolipids found in nerve cell membranes. These tests help diagnose neuropathies and autoimmune disorders affecting the nervous system.

What is GD1b antibody?

GD1b antibody is an antibody that targets GD1b gangliosides, a specific type of ganglioside molecule. It is often associated with autoimmune neuropathies, including Guillain-Barré syndrome (GBS).

What disease has anti ganglioside antibodies?

Diseases associated with anti-ganglioside antibodies include Guillain-Barré Syndrome (GBS) and Miller Fisher Syndrome (MFS).

What antibodies are tested for GBS?

In GBS, antibodies against gangliosides like GM1, GD1a, and GQ1b are tested to help diagnose the condition.

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