Liquid  Biopsy Test To Detect Cancer Cells or DNA

Liquid Biopsy Test To Detect Cancer Cells or DNA

A liquid biopsy is a blood test that helps detect and monitor cancer without the need for invasive procedures. It provides valuable information about the presence and progression of cancer.

 

Liquid Biopsy Test

Here are the basic details of the Liquid Biopsy Test.

Also Known As Blood-Based Cancer Test
Type Non-invasive diagnostic blood test
Purpose Detect, monitor, and guide cancer treatment
Sample Type Whole blood
Preparation No
Fasting Required Not required
Gender Unisex
Age Group All
Normal Value Negative
Reporting Time Several days to a week
Cost 20000-30000 INR*

*Liquid Biopsy Test Price range may vary as per location, lab type, and procedure of lab test.

 

Liquid Biopsy Test Means

Liquid Biopsy Test analyzes blood for cancer markers, offering non-invasive cancer detection.

  • It provides insights into treatment strategies, tumor progression, and prognosis.
  • This test can replace invasive tissue biopsies for select cancer monitoring.
  • Liquid Biopsy Test enhances precision medicine, guiding personalized cancer therapies.
  • It's a valuable tool in early cancer detection and monitoring treatment response.

 

Liquid Biopsy Test Purpose

The purpose of the Liquid Biopsy Test is to:

  • Liquid Biopsy Test aids in cancer diagnosis by detecting tumor markers in blood.
  • It helps monitor cancer treatment progress, guiding therapy adjustments.
  • Liquid Biopsy Test predicts treatment response and assesses prognosis.
  • This non-invasive test enhances precision medicine for personalized care.
  • It's a valuable tool for early cancer detection and disease progression tracking.

Liquid Biopsy Test_ Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

Liquid Biopsy Test Preparation

Here is the basic preparation for the Liquid Biopsy Test.

 

Before Test

  • No special preparation is typically needed for a liquid biopsy.
  • Consult your healthcare provider for any necessary medication adjustments.
  • Follow any specific instructions provided by your doctor.

 

During Test

  • A blood sample is collected from a vein, similar to a routine blood test.
  • The procedure is minimally invasive and relatively quick.
  • It's generally well-tolerated and does not require anesthesia.

 

After Test

  • There are typically no specific post-test precautions or actions required.
  • You can usually resume your regular activities immediately.
  • Your healthcare provider will discuss the results and any necessary follow-up steps with you.

 

Liquid Biopsy Test Procedure

Here is the basic Liquid Biopsy Test Procedure.

  • A blood sample is drawn from a vein, typically in the arm.
  • The blood sample is processed in a laboratory.
  • Tumor markers, such as circulating tumor cells or tumor DNA, are analyzed.
  • Medical professionals interpret the results for diagnosis, prognosis, and treatment guidance.
  • The results are discussed with the patient, and further steps are determined if necessary.

 

Liquid Biopsy Test Result

  • Interpret tumor marker levels for diagnosis and prognosis.
  • Assess potential treatment response and therapy adjustments.
  • Discuss results with the patient, guiding next steps as needed.

 

Liquid Biopsy Test Normal Result

Here is the normal range of the Liquid Biopsy Test.

Liquid Biopsy Test Results Normal Result
CTCs or ctDNA Presence Negative
ctDNA Genetic Errors Not Detected

In a normal result for a liquid biopsy test, the presence of circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) is typically negative. The test does not identify a specific cancer type, and common genetic errors associated with cancer are not detected.

 

Liquid Biopsy Test Interpretation

Here is the Interpretation of the Liquid Biopsy Test.

Result Interpretation
Positive for CTCs The presence of circulating tumor cells in the blood, is possibly related to cancer.
Negative for CTCs Absence of detectable circulating tumor cells, indicating no evidence of tumor cells in the blood.
Positive for ctDNA Detection of cancer-associated genetic errors or mutations in circulating tumor DNA.
Negative for ctDNA No cancer-specific genetic errors were detected in circulating tumor DNA.
Inconclusive Results do not provide a clear positive or negative outcome, further evaluation may be required.

Liquid biopsy test results can help detect and monitor cancer through the analysis of circulating tumor cells and tumor DNA, offering insights into cancer type and genetic errors.

 

Liquid Biopsy Test Positive Result

Here are the potential causes of positive Liquid biopsy Test results:

Positive Result Causes Description
Presence of Tumor Cells Indicates the possible presence of circulating tumor cells.
Detection of ctDNA Mutations Suggests cancer-related genetic mutations in circulating DNA.
Response to Treatment May show effective cancer treatment targeting tumor markers.
Disease Progression Implies cancer progression with increased tumor-related markers.

A positive result in a liquid biopsy test may indicate the presence of tumor cells, ctDNA mutations, treatment response, or disease progression.

 

Liquid Biopsy Test Negative Result

Here are potential causes of negative Liquid biopsy Test results:

Possible Causes Description
Absence of Tumor Cells The negative result suggests no circulating tumor cells detected in the blood.
No ctDNA Mutations Indicates the absence of cancer-related genetic mutations in circulating DNA.
Effective Treatment May mean cancer treatment has successfully targeted tumor markers.
Early Disease Stage A negative result might indicate early-stage cancer.

A negative result in a liquid biopsy test may signify the absence of tumor cells or cancer-related genetic mutations.

 

Specimen Requirements For Liquid Biopsy Test

Here are the specimen requirements for the Liquid Biopsy Test.

Specimen

Whole blood

Volume

2 tubes of 10 mL each

Container

Liquid Biopsy Specimen Kit

Collection

Collect 10 mL of whole blood into each of 2 Streck tubes supplied in the Liquid Biopsy Specimen Kit.

Storage

Room temperature

Sample Stability

Temperature

Period

Room temperature

7 days

Refrigerated

0 days

Frozen

0 days

Causes for Rejection

Samples not in Streck tubes, expired/incorrect tubes, insufficient quantity, delay >7 days, or frozen specimens.

 

Liquid Biopsy Test is Safe?

Liquid Biopsy is generally considered safe and minimally invasive.

  • Carries lower risks compared to traditional biopsies.
  • Possible mild side effects, such as bruising or discomfort.
  • Safe for patients with conditions that preclude surgery.
  • Risks associated with blood collection are minimal.

 

When Do You Get Liquid Biopsy Test Results? 

  • Turnaround time varies but typically takes several days.
  • May extend to over a week, depending on the laboratory.
  • Specialized reference labs may process the samples.
  • Results availability depends on the specific test and lab.
  • Consult with your healthcare provider for result timing.

 

Liquid Biopsy Test Limitation

Here is the basic limitation of the Liquid Biopsy Test.

  • Limited to certain cancer types and applications.
  • False negatives and positives can occur.
  • Sensitivity may vary depending on the cancer stage.
  • Tumor markers may not be present in all cases.
  • Clinical utility and long-term outcomes require further study.

 

Liquid Biopsy Test Risk Factors

Here are some of the risk factors of the Liquid Biopsy Test.

  • Minimal risk compared to surgical biopsies.
  • Potential for mild side effects like bruising.
  • Infection risk at the blood draw site is extremely low.
  • No exposure to radiation, reducing associated risks.
  • Overall, a safe diagnostic option for cancer.

 

Doctor Recommendations After Liquid Biopsy Test Result

 Here are the Doctor's recommendations or consult a specialist after the Liquid Biopsy Test.

Liquid Biopsy Result Doctor to Visit Reason to See Doctor
Positive Oncologist Discuss treatment.
Negative Follow-up care Review health status.

 

Liquid Biopsy Test Price

Here are the estimated Liquid Biopsy Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

20000-30000

New Delhi

20000-30000

Bangalore

20000-30000

Hyderabad

20000-30000

Kolkata

20000-30000

Pune

20000-30000

Lucknow

20000-30000

Noida

20000-30000

Surat

20000-30000

Gurugram

20000-30000

Patna

20000-30000

Chennai

20000-30000

Jaipur

20000-30000

Ahmedabad

20000-30000

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, Liquid biopsy tests analyze blood for tumor markers, aiding cancer detection, treatment guidance, and prognosis assessment in a minimally invasive and safe manner. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Liquid Biopsy - Wikipedia [1].
  • Liquid biopsy of cancer - NIH [2].
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FAQ

Can Liquid Biopsy detect heart failure?

Liquid Biopsy can provide insights into heart failure by analyzing specific biomarkers associated with the condition. While it may not be a primary diagnostic tool for heart failure, it can offer valuable information for assessing disease progression and treatment responses.

What is a Liquid Biopsy Test?

A Liquid Biopsy Test is a non-invasive diagnostic procedure that detects genetic alterations and biomarkers in a patient's bodily fluids, typically blood. This innovative test is used to identify and monitor various diseases, including cancer. It offers a less invasive alternative to traditional tissue biopsies, making it a valuable tool in early disease detection and treatment monitoring.

How does a Liquid Biopsy work?

Liquid Biopsy works by analyzing circulating free DNA (cfDNA), circulating tumor cells (CTCs), or other biomarkers present in bodily fluids. In the case of cancer, it can detect specific genetic mutations or alterations associated with the disease. This information provides insights into the presence, progression, and treatment response of cancer or other conditions.

How long does it take to get results from a Liquid Biopsy?

The turnaround time for Liquid Biopsy results can vary but is generally quicker than traditional biopsies. Results may be available within a few days to a few weeks, depending on the specific test and the testing facility.

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