• Drlogy Plus
Home/Medical Dictionary/AAT deficiency

AAT deficiency

An inherited condition in which the body either does not make enough of a protein called alpha-1 antitrypsin (AAT) or makes an abnormal form of AAT. AAT is made in the liver and helps protect the body’s organs, especially the liver and lungs, from damage. AAT deficiency can lead to serious lung conditions (including emphysema and bronchiectasis) and liver conditions (including cirrhosis, hepatitis, and liver cancer). It may also cause inflammation of the blood vessels and a rare skin condition that causes painful lumps on or under the skin. Lung problems caused by AAT deficiency almost always occur in adults, but liver and skin problems may occur in both adults and children. AAT deficiency is caused by a mutation (change) in a gene called SERPINA1. Also called alpha-1 antitrypsin deficiency.

Explore Medical Terms

20000+ Medical & Health Terms for Doctors, students & patients from a medical dictionary. Our experts define difficult medical & health language in easy-to-understand explanations of each and every medical term.

Medical & Health Terms online medical dictionary provides quick & easy access to hard-to-spell and often misspelled medical & health definitions through an extensive alphabetical A-Z listing.

DOCTOR'S MOST TRUSTED HEALTHCARE PLATFORM

10M+

Patients

30000+

Doctors

25000+

Hospitals/Labs

Dictionary

Abbreviation

App

Health

Plus